洞察前沿，连接科研新知

完整作者

Tamrin Chowdhury、C Mircea S Tesileanu、Emre Kocakavuk、Kevin C Johnson、Joo Ho Lee、Zeynep Erson-Omay、Chaewon Heo、Kenneth Aldape、Samirkumar B Amin、Kevin J Anderson、David M Ashley、Floris P Barthel、Jill S Barnholtz-Sloan、Daniel J Brat、Andrew R Brodbelt、Ana Valeria Castro、Elizabeth B Claus、Jennifer M Connelly、Joseph F Costello、Indrani Datta、Carol Elliott、Gaetano Finocchiaro、Pim J French、Hui K Gan、Luciano Garofano、Padmaja L Ghospurkar、Anna Golebiewska、Pranav S Gundla、Beth Hermes、Chibo Hong、Youri Hoogstrate、Craig Horbinski、Jason T Huse、Antonio Iavarone、Cihat Karadag、Mustafa Khasraw、Mathilde C M Kouwenhoven、Peter S LaViolette、Kay Li、Allison Lowman、Katy McCortney、Hyo-Eun Moon、Nader Sanai、MacLean P Nasrallah、H K Ng、D Ryan Ormond、Bethany Kwan、Marta Padovan、Sun Ha Paek、Laila M Poisson、Sushant Puri、Erica Shen、Shwetal Mehta、Andrew E Sloan、Wies R Vallentgoed、Erwin G Van Meir、Rachael Vaubel、Taylor E Wade、Annemiek M E Walenkamp、Colin Watts、Tobias Weiss、Michael Weller、Pieter Wesseling、Kerryn Westcott、Bart A Westerman、Gordon Y Ye、W K Alfred Yung、GLASS Consortium、Frederick S Varn、Roel G W Verhaak

作者机构

• Department of Neurosurgery, Yale University, New Haven, CT, USA.
• Department of Hematology and Stem Cell Transplantation, West German Cancer Center (WTZ), National Center for Tumor Diseases (NCT) West, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
• Department of Radiation Oncology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea.
• Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
• National Institutes of Health, Bethesda, MD, USA.
• The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
• Preston Robert Tisch Brain Tumor Center at Duke University, Durham, NC, USA.
• Translational Genomics Research Institute, Phoenix, AZ, USA.
• National Cancer Institute, Bethesda, MD, USA.
• Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
• Walton Centre NHS Foundation Trust, Liverpool, UK.
• Hermelin Brain Tumor Center, Department of Neurosurgery, Henry Ford Health, Detroit, MI, USA.
• Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
• Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA, USA.
• Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.
• Department of Neurosurgery, University of California, San Francisco, San Francisco, CA, USA.
• St Joseph's Hospital and Medical Center, Phoenix, AZ, USA.
• Department of Neurology, IRCCS Ospedale San Raffaele, Milan, Italy.
• Department of Neurology, Erasmus University Medical Centre Rotterdam, Rotterdam, The Netherlands.
• Cancer Therapies and Biology Laboratory, Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Victoria, Australia.
• Department of Public Health Sciences, Division of Biostatistics and Bioinformatics, Miller School of Medicine, University of Miami, Miami, FL, USA.
• Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA.
• NORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg.
• Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
• University of Texas MD Anderson Cancer Center, Houston, TX, USA.
• Department of Neurological Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.
• Department of Neurosurgery, Duke University Medical Center, Durham, NC, USA.
• Department of Neurology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
• Department of Radiology, Medical College of Wisconsin, Milwaukee, WI, USA.
• Department of Pathology, Prince of Wales Hospital, Hong Kong, China.
• Department of Neurosurgery, Cancer Research Institute, Hypoxia/Ischemia Disease Institute, Seoul National University, Seoul, Republic of Korea.
• Ivy Brain Tumor Center at the Barrow Neurological Institute, Phoenix, AZ, USA.
• Glioblastoma Translational Center of Excellence, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
• Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
• Department of Neurosurgery, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.
• Department of Emergency Medicine, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.
• Advanced Institutes of Convergence Technology, Seoul National University, Suwon-si, Republic of Korea.
• Oregon Health & Science University, Portland, OR, USA.
• Neurological Institute, Premier Health and Wright State University School of Medicine, Dayton, OH, USA.
• University of Alabama at Birmingham (UAB), Birmingham, AL, USA.
• Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA.
• Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
• Department of Cancer Genome Sciences, University of Birmingham, Birmingham, UK.
• Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
• VUmc, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
• Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
• Department of Neurosurgery, VUmc, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
• University of California, San Diego, La Jolla, CA, USA.
• Department of Neuro-Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
• The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. frederick.varn@jax.org.
• Department of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, CT, USA. frederick.varn@jax.org.
• Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA. frederick.varn@jax.org.
• Department of Neurosurgery, Yale University, New Haven, CT, USA. roel.verhaak@yale.edu.

技术路线

['数据/样本：183例IDH突变型胶质瘤患者的纵向收集肿瘤标本（来自GLASS联盟）', '分析：全基因组测序和全外显子组测序，表征纵向标本的遗传驱动因素；验证已知进展基因组标志物（超突变、CDKN2A/B纯合缺失），发现区分星形细胞瘤与少突胶质细胞瘤演化轨迹的遗传改变；分析获得性改变、全基因组变化与患者结局的趋同；关联治疗（替莫唑胺、放疗）与突变特征', '验证：验证已知基因组标志物（超突变和CDKN2A/B纯合缺失）']

最近 5 个完整年度引用趋势

完整作者

暂未整理

作者机构

暂未整理

技术路线

暂未整理

最近 5 个完整年度引用趋势

暂无引用数据

完整作者

Ahmed Reda Bahr、Youssef Basem、Amani Alhejely、Abdel Rahman Alaa、Saifallah Mabrouk Abozeid、Amira Basem、Mohsen A Khormi、Mabrouk A Abo-Zaid

作者机构

• Faculty of Medicine, Alexandria University, Alexandria, Egypt.
• Medical and Pharmaceutical Industrial Biotechnology Department, College of Biotechnology, Misr University for Science and Technology (MUST), Giza, Egypt.
• Biology Department, Darb University College, Jazan University, Jazan, Saudi Arabia.
• Faculty of Medicine, Cairo University, Kasr AlAiny, Egypt.
• Department of Biotechnology and Genetic Engineering, College of Science, Helwan National University, Cairo, Egypt.
• Department of Biology, College of Science, Jazan University, Jazan, Saudi Arabia.

技术路线

暂未整理

最近 5 个完整年度引用趋势

暂无引用数据

完整作者

Venise Jan Castillon、Amy X Xie、Sonia Boscenco、Ethan Tse、Neil Ruthen、Jamie Wang、Ziad Bakouny、Michele Waters、Chenlian Fu、Christopher Fong、Mustafa Saleh、Tarek Baroud、Wungki Park、Urvi A Shah、A Ari Hakimi、Puneeth Iyengar、Justin Jee、Eileen White、Alexander Gusev、Tobias Janowitz、Marcus D Goncalves、Ed Reznik

作者机构

• Computational Oncology Service, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
• Dana-Farber Cancer Institute, Boston, MA, USA.
• Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
• Weill Cornell Medical College, New York, NY, USA.
• Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
• Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
• Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
• Rutgers Cancer Institute, Rutgers University, New Brunswick, NJ, USA.
• Ludwig Princeton Branch, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA.
• Broad Institute of MIT and Harvard, Cambridge, MA, USA.
• Harvard Medical School, Boston, MA, USA.
• Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
• Northwell Health Cancer Institute, Northwell Health, New Hyde Park, NY, USA.
• Holman Division of Endocrinology, Diabetes & Metabolism, Department of Medicine and Radiation Oncology, NYU Langone Health, New York, NY, USA.
• Computational Oncology Service, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. reznike@mskcc.org.

技术路线

纵向临床基因组数据（MSK-IMPACT，52,236例患者，2010-2024）→定义共识性恶病质体重减轻的发作分辨轨迹并关联结局、血清学与肿瘤基因型→多变量模型预测肺癌、结直肠癌和前列腺癌的恶病质体重减轻风险→在Dana-Farber癌症研究所独立外部队列（n=5,785）中验证

最近 5 个完整年度引用趋势

完整作者

Lupeng Ji、Xue Zhou、Jiong Gao、Lin Zhu、Hui Zhang、Yilong Tu、Shun Ge、Chao Yuan

作者机构

• Department of Pathology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China.
• Medical Affairs Department, Hangzhou Adicon Clinical Laboratories Co., Ltd., West Lake District, Hangzhou, China.
• Medical Affairs Department, Shenzhen Mindray Bio-Medical Electronics Co, Ltd, Shenzhen, China.

技术路线

文献检索（PubMed/MEDLINE、Web of Science Core Collection、Google Scholar）→叙述性综述证据综合（外显子组重分析、变异重分类、动态报告及补充诊断方法）

最近 5 个完整年度引用趋势

暂无引用数据

完整作者

Anqi Dai、Annamaria Ballweg、William Jogia、Madhumitha Rangesa、Peter A Adintori、Mirae Baichoo、Tyler Funnell、Teng Fei、Nicholas R Waters、Abrielle Swartz、Sukanya Sahu、Brianna Gipson、Sandeep S Raj、Eiko Hayase、Zoe Pierce、Kenton Wu、Natalie Smith、Justin Neuberger、Adam Warren、Marina Burgos da Silva、Oriana Miltiadous、Corrado Zuanelli Brambilla、Marissa Lubin Buchan、Tatanisha K Peets、Ana Gradissimo、Luigi A Amoretti、Caichen Duan、Chenzhen Zhang、Fanny Matheis、Alexis P Sullivan、John B Slingerland、Annelie G Clurman、Daniel G Brereton、Paul A Giardina、Antonio L C Gomes、Abigail J Johnson、Dan Knights、Robert R Jenq、Kate A Markey、Miguel-Angel Perales、Sergio A Giralt、Marcel R M van den Brink、Jonas Schluter、Jonathan U Peled

作者机构

• Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
• Institute for Systems Genetics, NYU Langone Health Grossman School of Medicine, New York, NY, USA.
• Department of Microbiology, NYU Langone Health Grossman School of Medicine, New York, NY, USA.
• Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Los Angeles, CA, USA.
• Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
• Departments of Genomic Medicine and Stem Cell Transplantation Cellular Therapy, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
• Human Oncology & Pathogenesis Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
• Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
• Haematology Unit, Department of Cellular Therapy, Hematology and Laboratory Medicine, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.
• Food and Nutrition Services, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
• Department of Biomedical Engineering, NYU Tandon School of Engineering, New York, NY, USA.
• Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
• Riddet Institute, Massey University, Palmerston North, New Zealand.
• Department of Computer Science and Engineering, University of Minnesota, Minneapolis, MN, USA.
• Biotechnology Institute, University of Minnesota, Saint Paul, MN, USA.
• Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
• Division of Medicine, University of Washington, Seattle, WA, USA.
• Weill Cornell Medical College, New York, NY, USA.
• City of Hope, Duarte, CA, USA. mvandenbrink@coh.org.
• Institute for Systems Genetics, NYU Langone Health Grossman School of Medicine, New York, NY, USA. jonas.schluter@nyulangone.org.
• Department of Microbiology, NYU Langone Health Grossman School of Medicine, New York, NY, USA. jonas.schluter@nyulangone.org.
• Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA. jonas.schluter@nyulangone.org.
• Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. peledj@mskcc.org.
• Weill Cornell Medical College, New York, NY, USA. peledj@mskcc.org.

技术路线

数据/样本：173例造血干细胞移植住院患者的9,419餐饮食记录及纵向肠道菌群样本（其中158例有配对纵向菌群样本用于贝叶斯推断）；分析：贝叶斯推断评估饮食与菌群动态关系；验证：小鼠实验验证蔗糖补充对抗生素诱导肠球菌扩张的影响。

最近 5 个完整年度引用趋势

完整作者

Lu Yang、Vaidhvi Singh、Brent J Gawey、Jason P Sinnwell、Stephen Johnson、Elle C Billings、Trena M Van Gorp、Jonathan J Harrington、Michael Q Slama、Lisa M Till、Manavjot Singh、Thoshik R Samineni、Mojun Zhu、Krishna R Kalari、Gianrico Farrugia、Jun Chen、Ruben A T Mars、Purna C Kashyap

作者机构

• Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA; The Benioff Center for Microbiome Medicine, University of California San Francisco, San Francisco, CA, USA.
• Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
• Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, MN, USA; Division of Gastroenterology, Mount Sinai, New York, NY, USA.
• Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
• Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
• Division of Gastroenterology, Mount Sinai, New York, NY, USA.
• Department of Oncology, Mayo Clinic, Rochester, MN, USA.
• Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, MN, USA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
• Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA; Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA. Electronic address: chen.jun2@mayo.edu.
• Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, MN, USA; Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA. Electronic address: mars.ruben@mayo.edu.
• Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, MN, USA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. Electronic address: kashyap.purna@mayo.edu.

技术路线

真实世界混合癌症队列（1364例癌症患者和287例健康对照）的粪便微生物组数据 → 构建校正框架以排除与合并症、人口学和临床变量的非特异性关联，鉴定出五类癌症相关的341个菌种

最近 5 个完整年度引用趋势

完整作者

Markus Perl、Severin Guetter、Dhyani Shah、Simon Holzinger、Luisa Becker、Misbah Tariq、Philipp Menauer、Simon Delahais、Gloria Lutzny-Geier、Julian N Scherer、Sascha Göttert、Konstantin Herfeld、Paul Heinrich、Klaus Georg Kreitmeier、Claudia Gebhard、Wolfgang Herr、Marcel P Trefny、Janina Doerr、Saba Sameri、Dennis C Harrer、Kai Ziegler-Martin、Sarah Staudt、Leo Hansmann、Matthias Edinger、Daniel Wolff、Daniela Weber、Elisabeth Meedt、Alexander Denk、Andre Gessner、Ernst Holler、Tobias Wertheimer、Klaus Neuhaus、Tingting Zheng、David M Cordas Dos Santos、Sebastian Theurich、Melanie Schirmer、Karin Kleigrewe、Jonas Schluter、Marcel van den Brink、Michael Schmitt、Markus Feuerer、Christoph Heuser-Loy、Jeremy Baldwin、Luca Gattinoni、Michael Rehli、Michael Hudecek、Camille Bigenwald、Laurence Zitvogel、Marion Subklewe、Viktoria Blumenberg、Maria-Luisa Schubert、Christoph Stein-Thoeringer、Maik Luu、Sebastian Kobold、Matthias A Fante、Erik Thiele Orberg、Hendrik Poeck

作者机构

• Department of Internal Medicine III, Hematology & Internal Oncology, University Hospital Regensburg, Regensburg, Germany; Bavarian Cancer Research Center (BZKF), Regensburg, Germany. Electronic address: markus.perl.ukr@gmail.com.
• Department of Internal Medicine III, Hematology & Internal Oncology, University Hospital Regensburg, Regensburg, Germany; Leibniz Institute for Immunotherapy (LIT), Regensburg, Germany.
• Department of Internal Medicine III, Hematology & Internal Oncology, University Hospital Regensburg, Regensburg, Germany.
• Division of Clinical Pharmacology, Department of Medicine IV, University Hospital, Ludwig Maximilian University (LMU) of Munich, Munich, Germany.
• Department of Internal Medicine 5, Hematology and Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
• Leibniz Institute for Immunotherapy (LIT), Regensburg, Germany.
• Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.
• Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.
• Division of Hematology and Oncology, Department of Medicine, Freiburg University, Freising, Germany.
• Core Facility Microbiome, ZIEL - Institute for Food & Health, Technische Universität München, Freising, Germany.
• Translational Microbiome Data Integration, School of Life Sciences, Technical University of Munich, Freising, Germany; ZIEL - Institute for Food & Health, Technische Universität München, Freising, Germany.
• Gene Center and Department of Biochemistry, LMU Munich, Munich, Germany.
• Department of Medicine III, Hematology/Oncology, LMU University Hospital and Gene Center, LMU Munich, Munich, Germany; German Cancer Consortium (DKTK), Partner Site Munich, a partnership between the DKFZ and BZKF at the University Hospital of the LMU, Germany.
• Translational Microbiome Data Integration, School of Life Sciences, Technical University of Munich, Freising, Germany; ZIEL - Institute for Food & Health, Technische Universität München, Freising, Germany; Center for Organoid Systems, Technical University Munich, Garching, Germany.
• Bavarian Center for Biomolecular Mass Spectrometry, TUM School of Life Sciences, Technical University Munich, Freising, Germany.
• Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA; Institute for Systems Genetics, NYU Langone Health Grossman School of Medicine, New York, NY, USA.
• Beckman Research Institute, City of Hope, Duarte, CA, USA.
• Department of Medicine V, Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.
• Leibniz Institute for Immunotherapy (LIT), Regensburg, Germany; Department of Internal Medicine III, Haematology and Oncology, University Hospital Bonn, Bonn, Germany.
• Lehrstuhl für Zelluläre Immuntherapie, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany; Branch Cellular Immunotherapy, Fraunhofer Institute for Cell Therapy and Immunology (IZI), Würzburg, Germany.
• Gustave Roussy Cancer Campus, Villejuif, France.
• Department of Medicine III, Hematology/Oncology, LMU University Hospital and Gene Center, LMU Munich, Munich, Germany; Laboratory for Translational Cancer Immunology, Gene Center LMU Munich, Munich, Germany; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany; Bavarian Cancer Research Center (BZKF), Munich, Germany.
• Department of Internal Medicine I, University Hospital Tuebingen, Tuebingen, Germany.
• Division of Clinical Pharmacology, Department of Medicine IV, University Hospital, Ludwig Maximilian University (LMU) of Munich, Munich, Germany; Laboratory for Translational Cancer Immunology, Gene Center LMU Munich, Munich, Germany; Bavarian Cancer Research Center (BZKF), Munich, Germany; German Center for Lung Research (DZL), Partner Site Munich, Munich, Germany.
• Department of Internal Medicine III, Hematology & Internal Oncology, University Hospital Regensburg, Regensburg, Germany; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.
• Department of Internal Medicine III, Hematology & Internal Oncology, University Hospital Regensburg, Regensburg, Germany; Bavarian Cancer Research Center (BZKF), Regensburg, Germany. Electronic address: erik.orberg@ukr.de.
• Department of Internal Medicine III, Hematology & Internal Oncology, University Hospital Regensburg, Regensburg, Germany; Bavarian Cancer Research Center (BZKF), Regensburg, Germany; Leibniz Institute for Immunotherapy (LIT), Regensburg, Germany. Electronic address: hendrik.poeck@ukr.de.

技术路线

粪便宏基因组与靶向质谱（129例三中心队列）→代谢物与疾病进展关联分析→人及小鼠CAR-T细胞模型功能验证

最近 5 个完整年度引用趋势

完整作者

Chang-Lin Yang、Rui Yang、Wen-Lu Tan、Han-Xiao Zhou、Ling-Xiang Wu、Ji Shi、Fan Wu、Li-Jie Huang、Zhi-Yan Sun、Tao Jiang、Zheng Zhao

作者机构

• Beijing Neurosurgical Institute, Capital Medical University, Beijing 100070, China.
• Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.
• Chinese Glioma Genome Atlas (CGGA) Network and Asian Glioma Genome Atlas (AGGA) Network, Beijing 100070, China.
• Chinese Neuro-Oncology Genome Atlas (CGGA-CNS) Network, Beijing 100070, China.

技术路线

数据/样本：文献人工审编的circRNA-疾病关联，v3.0含15,390条条目（9,168个circRNA、656个MONDO标准化疾病术语、66个物种），并整合TCGA 33个癌症队列的2,962,504条circRNA-癌症队列记录（Circ2CNV模块）和2,025条细胞类型分辨证据（29种细胞类型，Circ2Celltype模块）；分析：依据临床证据、circular-transcript身份验证、表达检测、功能实验、分子机制验证和生物信息学分析等支持证据的强度与多样性，为每条记录赋予置信度评分，并整合基因组坐标、亚细胞定位、实验验证方法、临床意义、数据与代码可及性及多疾病术语交叉引用；验证：原文未报告独立的实验或计算验证。

最近 5 个完整年度引用趋势

完整作者

Shangtao Wang、Jinling Zhang、Wenshuang Wang、Sihan Xu、Man Zhang、Yuanyuan Hou、Gang Bai

作者机构

• College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research. State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300350, China.

技术路线

暂未整理

最近 5 个完整年度引用趋势

暂无引用数据